Buy Livagen Online (5mg / 10mg / 20mg) | Synthetic Hepatic Bioregulator

When researchers in cell biology and epigenetics seek to buy Livagen online to evaluate nuclear chromatin activation and hepatic metabolic pathways, securing sequence accuracy without truncated impurities is essential. ABZ Bio Lab supplies analytical-grade Livagen reference standard (CAS 162142-65-8) manufactured to a strict purity benchmark of ≥99.2% HPLC purity.

Livagen is a synthetic short-chain peptide bioregulator consisting of four amino acids: L-Lysine, L-Glutamic acid, L-Aspartic acid, and L-Proline ($\text{Lys-Glu-Asp-Pro}$). Structurally related to Epithalon and other Khavinson peptide bioregulators, Livagen acts directly on nuclear chromatin. In elderly lymphocyte cultures and damaged hepatocyte lines, Livagen has been shown to induce heterochromatin decondensation, reactivating silenced genes and restoring youthful levels of protein synthesis and cellular metabolism.

Every 3ml vial contains a uniform white lyophilized cake sealed under negative pressure with a self-healing rubber stopper and flip-off cap, guaranteeing maximum stability during bench handling and reconstitution.

Key Research Focus Areas

• Chromatin Remodeling & Gene Reactivation: Evaluates the decondensation of pericentromeric heterochromatin in senescent lymphocyte and hepatocyte cell cultures.

• Hepatic Metabolic Function: Measures transcriptional regulation of protein synthesis and liver enzyme activity under toxic or metabolic stress models in vitro.

• Immune & Lymphocyte Reactivation: Investigates activation of ribosomal genes and histone modifications in aging immune cell models.

• Bioregulator Structural Distinction:

  • Livagen ($\text{Lys-Glu-Asp-Pro}$): 4-amino-acid peptide focused on hepatic and chromatin regulation ($461.47\text{ Da}$).

  • Epithalon ($\text{Ala-Glu-Asp-Gly}$): 4-amino-acid peptide targeting telomerase induction and pineal signaling.

  • Cartalax ($\text{Ala-Glu-Asp}$): 3-amino-acid tripeptide targeting cartilage and extracellular matrix models.

Quality Standards & Testing

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                    ANALYTICAL TESTING BENCHMARKS
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 Quality Metric         Testing Methodology         Pass Benchmark
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 Chemical Purity         RP-HPLC Peak Area Analysis ≥ 99.2% Main Peak
 Mass Identification    LC-MS Electrospray          461.47 Da (± 0.5 Da)
 Peptide Content         Elemental Nitrogen Assay   ≥ 85.0% Net Content
 Endotoxin Load         LAL Chromogenic Assay       < 0.25 EU/mg
 Residual Moisture       Karl Fischer Titration     < 3.0% Residual Moisture
================================================================================

Storage & Reconstitution Directives

• Dry Lyophilized Cake: Store unopened 3ml vials at -20°C (stable up to 24 months). Short-term bench storage at 2°C to 8°C.

• Reconstitution Method: Allow vial to reach room temperature to prevent condensation. Slowly add solvent along the inner glass wall. Swirl gently until dissolved—do not agitate or shake violently.

• Reconstituted Stability: Keep liquid preparations refrigerated at 2°C to 8°C and complete testing protocols within 21 to 28 days.