Buy Purified Guaiacol Online | High-Purity 2-Methoxyphenol Reference Standard
Guaiacol (2-Methoxyphenol, CAS 90-05-1) is a purified, liquid aromatic compound used extensively as an analytical reference standard and key chemical intermediate in laboratory research. Naturally occurring as a thermal breakdown product of lignin and synthesized in various botanical genera (such as Guaiacum), Guaiacol serves as a fundamental building block in organic chemistry. Modern organic pathways utilize Guaiacol as a precursor in the production of vanillin involving glyoxylic acid condensation to mandelic acid derivatives followed by oxidation and decarboxylation as well as eugenol and allied phenolic structures.
In quantitative laboratory workflows, analytical pre-treatments and solvent formulations often require precise dilution protocols. Reagents like Bacteriostatic Water or 0.6% Acetic Acid Solution are frequently integrated into secondary aqueous buffer systems to calibrate pH and ionic strength. Researchers profiling cellular stress pathways and tissue regeneration mechanisms frequently evaluate Guaiacol’s radical scavenging activity alongside control peptides like the BPC-157 Reference Standard or GHK-Cu Copper Tripeptide. All orders are managed under ABZ Bio Lab’s standard Terms and Conditions and dispatched rapidly via our Shipping Policy.
In Vitro Research Applications of Guaiacol
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Organic Precursor & Chemical Synthesis Modeling: Acts as an essential phenolic substrate for the multi-step synthetic pathway yielding vanillin, eugenol, and related bio-aromatic derivatives in chemical research.
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Reactive Oxygen Species (ROS) & Radical Scavenging Assays: Utilized in spectrophotometric assays to measure free radical neutralization kinetics and quantify cellular antioxidant capacity in cell culture models.
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Structural Comparison with Auxiliary Chemical Probes:
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Guaiacol: A monophenolic 2-methoxyphenol reagent utilized for ROS scavenging, radical quench assays, and aromatic precursor chemistry.
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Pinealon Reference Standard: A short-chain synthetic peptide model evaluated for cellular gene expression and nuclear signaling.
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Epithalon Reference Standard: A synthetic peptide reference standard evaluated in longevity and telomerase expression models.
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Quality Control: Batch GC & HPLC Verification
Every batch of purified Guaiacol undergoes rigorous gas chromatography and mass spectrometry testing to ensure high chemical purity, low moisture content, and absence of secondary oxidation products.
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ANALYTICAL TESTING BENCHMARKS
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Test Metric Testing Methodology Pass Benchmark
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Chemical Purity GC-FID Peak Area Analysis ≥ 99.5% Main Peak
Mass Verification GC-MS / LC-MS 124.14 Da (± 0.5 Da)
Refractive Index Abbe Refractometer 1.543 – 1.545 at 20°C
Water Content Karl Fischer Titration ≤ 0.20%
Physical Appearance Visual Inspection Clear, Colorless to Light Yellow Liquid
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A batch-specific Certificate of Analysis (CoA) containing complete chromatographic data is supplied with every order. For technical inquiries regarding analytical validation, consult our Research Peptides FAQ or contact our laboratory support desk directly through Contact ABZ Bio Lab.
Technical Specification Matrix
| Quality Parameter | Analytical Benchmark & Standard |
| Product Name | Guaiacol Purified Reference Standard |
| Synonyms | 2-Methoxyphenol, o-Methoxyphenol, Pyrocatechol monomethyl ether |
| CAS Registry Number | 90-05-1 |
| Chemical Formula | C₇H₈O₂ |
| Molecular Mass | 124.14 g/mol |
| Purity Grade | ≥99.5% (GC-FID Peak Area Analysis) |
| Physical Appearance | Clear, colorless to pale amber liquid / low-melting solid |
| Density / Specific Gravity | ~1.129 g/mL at 25°C |
| Solubility Profile | Soluble in ethanol, ether, chloroform, and organic solvents; sparingly soluble in aqueous media |
| Documentation | GC Chromatogram & GC-MS Certificate of Analysis |
Handling, Reconstitution & Storage Parameters
To preserve chemical stability and prevent photo-oxidation:
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Unopened Liquid Storage: Store tightly sealed in dark amber glass bottles at 15°C to 25°C in a dry, well-ventilated laboratory area. Protect from direct ambient light, ignition sources, and strong oxidizing agents.
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Handling Parameters: Note that pure Guaiacol has a melting point of approximately 28°C; if solidification occurs at lower bench temperatures, warm the sealed container gently in a 30°C water bath until fully liquefied. Pipette under an operational fume hood using chemical-resistant equipment.
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Working Solution Stability: Aliquots diluted in organic solvents should be kept tightly capped in dark glass containers at 2°C to 8°C and used within active trial schedules. Review our full Refund Policy for dispatch quality standards.
Direct Warehouse Fulfillment & Ordering
ABZ Bio Lab maintains an efficient distribution and supply infrastructure servicing academic institutions, testing hubs, and industrial research laboratories:
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Central Logistics Operations: Orders are fulfilled directly from distribution hubs in London and Amsterdam to ensure rapid turnaround times and bypass customs delays across the UK and Europe.
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Thermal & Impact Packaging: Liquid units are secured in shock-absorbing, leak-proof outer packaging to guarantee safe delivery during transit.





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