Acetyl Coenzyme A (>83% enzymatic)

Price range: £31.00 through £330.00

Acetyl Coenzyme A Reference Standard (Trilithium Salt Format, CAS 75520-41-1 / 32140-51-5)

Analytical-grade metabolic cofactor and essential substrate for acetyltransferase enzyme kinetics, Krebs cycle biochemical modeling, and histone acetylation assays in cell-free and cell culture systems. Supplied as a highly soluble, freeze-dried powder with a guaranteed enzymatic purity benchmark of ≥83%.

  • Chemical Identity: Acetyl Coenzyme A Trilithium Salt | EC Number: 278-233-4

  • Molecular Weight: 827.37 g/mol | CAS Registry: 75520-41-1 / 32140-51-5 | Formula: $\text{C}_{23}\text{H}_{35}\text{Li}_3\text{N}_7\text{O}_{17}\text{P}_3\text{S}$

  • Format & Fill: 100mg, 500mg, 1g sterile vial (Lyophilized solid powder in USP Type I amber glass)

  • Enzymatic Assay Rating: ≥83% active substrate content (Batch-specific Certificate of Analysis provided)

  • Primary Application: Enzymatic acetylation assays, TCA cycle modeling, fatty acid oxidation kinetics, histone acetyltransferase (HAT) research

  • Compliance: Strictly For In Vitro Laboratory Research Use Only (RUO).

Buy Acetyl Coenzyme A Online | High-Purity Enzymatic Substrate Reference Standard

When analytical research laboratories and enzymatic testing facilities seek to buy Acetyl Coenzyme A for central metabolic modeling, securing batch-verified enzymatic activity and minimal moisture contamination is critical. ABZ Bio Lab supplies high-grade Acetyl Coenzyme A trilithium salt manufactured to a minimum purity threshold of ≥83% by enzymatic assay.

Acetyl Coenzyme A functions as a pivotal biochemical intermediate involved in the transfer of acetyl groups during cellular respiration, lipid synthesis, and epigenetic histone modifications. In cell-free and cell culture assays, this compound serves as the primary acetyl donor for choline acetyltransferase (ChAT), citrate synthase, and acetyl CoA carboxylase modeling. Solubilization protocols typically utilize aqueous laboratory vehicles or Bacteriostatic Water  for stock solution preparation. Laboratories frequently utilize Acetyl Coenzyme A alongside metabolic and short-chain bioregulator standards such as Pinealon or  Livagen  to evaluate gene transcription kinetics and cellular homeostasis.

In Vitro Research Applications of Acetyl Coenzyme A

Acetyl Coenzyme A is evaluated extensively across enzymology, bioenergetics, and epigenetic regulation research disciplines:

  • Enzymatic Acetylation Kinetics & HAT Assays: In vitro evaluation of histone acetyltransferase (HAT) activity, measuring nucleosomal core protein acetylation and epigenetic gene regulation in chromatin models.

  • TCA Cycle & Metabolic Pathway Profiling: Quantitative assessment of citrate synthase binding dynamics, ATP generation pathways, and fatty acid beta-oxidation flux in isolated mitochondrial suspensions.

  • Neurochemical Substrate Modeling: In vitro analysis of acetylcholine biosynthesis in neuronal cell line models through enzymatic interaction with choline acetyltransferase alongside non-invasive nootropic research models like Adamax Nasal Spray.

Quality Control: Batch HPLC & Enzymatic Verification

When evaluating Acetyl Coenzyme A prices across technical suppliers, batch-specific analytical proof is the key indicator of experimental reliability:

Plaintext

================================================================================
                    ANALYTICAL TESTING BENCHMARKS
================================================================================
 Test Metric             Testing Methodology        Pass Benchmark
--------------------------------------------------------------------------------
 Enzymatic Assay         Phosphotransacetylase Assay ≥ 83.0% Active Content
 Solubility (1% in H2O)  Visual Clarity Benchmark   Clear, Colourless Solution
 Loss on Drying          Thermogravimetric Analysis ≤ 5.0% Moisture Content
 Mass Verification       LC-MS / ESI-MS             827.37 Da (± 1.0 Da)
================================================================================

A batch-specific Certificate of Analysis (COA) detailing exact enzymatic assay values, moisture percentage, and structural identity accompanies every order. For more information regarding analytical quality assurance, consult our [Research Peptides FAQ].

Technical Specification Matrix

Quality Parameter Analytical Benchmark & Standard
Product Name Acetyl Coenzyme A 
Synonyms Acetyl-CoA trilithium salt, S-Acetyl coenzyme A
CAS Registry Number 75520-41-1 / 32140-51-5
EC Registry Number 278-233-4
Chemical Formula $\text{C}_{23}\text{H}_{35}\text{Li}_3\text{N}_7\text{O}_{17}\text{P}_3\text{S}$
Molecular Mass 827.37 g/mol
Enzymatic Assay Grade ≥83% (Enzymatic Assay)
Physical Appearance White to off-white lyophilized solid powder
Salt Format Trilithium salt format
Solubility Profile Soluble in water (Clear, colourless at 1% H2O) and aqueous solutions like Bacteriostatic Water
Documentation Technical Data Sheet (TDS) & Safety Data Sheet (SDS) COA

Handling, Reconstitution & Storage Parameters

To preserve enzymatic stability and prevent hydrolytic breakdown of the thioester bond:

  • Unopened Powder Storage: Store sealed vials at -20°C for extended shelf-life. Maintain under dry conditions and protect strictly from direct ambient light.

  • Reconstitution Guidelines: Bring vial to room temperature prior to opening. Dissolve in sterile deionized water or cold aqueous buffer. Avoid heating or exposing to basic pH levels (>7.5) to prevent hydrolysis of the acetyl-thioester bond.

  • Reconstituted Solution Stability: Keep liquid stock solutions frozen at -20°C in single-use aliquots. Avoid repeated freeze-thaw cycles.

Direct Warehouse Fulfillment & Ordering

ABZ Bio Lab operates a streamlined procurement system tailored for research institutes, universities, and commercial laboratories:

  • Central Logistics Operations: Dispensed and fulfilled directly from central distribution hubs in London and Amsterdam to ensure rapid, duty-free transit across UK and European markets. Review our  Research Product Shipping Policy for full transit timelines.

  • Thermal Shock Packaging & Compliance: Vials are packed inside shock-absorbing, thermally buffered outer packaging to guarantee chemical integrity upon delivery. Orders are strictly governed by our Terms and Conditions  and Research Product Refund Policy.

Quantity

100mg Vial, 500mg Vial, 1g Vial, 3 x 500mg Workstation Pack

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